TY - JOUR AU - Singh, Janardhan AU - Sangwan, Sukhbir Singh AU - Singh, Jarnail AU - Siwach, Ram Chandar AU - Shukla, Govind PY - 2017/01/31 Y2 - 2024/03/29 TI - An open labeled study to evaluate efficacy and safety of ampucare in patients with bedsore JF - International Journal of Basic & Clinical Pharmacology JA - Int J Basic Clin Pharmacol VL - 2 IS - 4 SE - Original Research Articles DO - UR - https://www.ijbcp.com/index.php/ijbcp/article/view/1283 SP - 371-374 AB - <p class="abstracttext"><strong><span lang="EN-IN">Background: </span></strong><span lang="EN-IN">To evaluate efficacy and safety of ampucare, a polyherbal product, in patients with bedsore.</span></p><p class="abstracttext"><strong><span lang="EN-IN">Methods</span></strong><span lang="EN-IN">: One hundred patients, either sex, more than 18 years of age, with bedsore were divided in to two groups of 50 each. Group-I- Served as control- povidone iodine solution was applied locally on the bedsore, once daily. Group- II- Treatment group- ampucare lotion was applied locally, once daily. Primary end point was time to wound healing and secondary end point included reduction in wound surface area at day-7 and at treatment completion. Percent patients cured, improved, or treatment failure were noted. Depth of wound, % healing and adverse effects were recorded.</span></p><p class="abstracttext"><strong><span lang="EN-IN">Results</span></strong><span lang="EN-IN">: Application of ampucare in patients with bedsore resulted in rapid healing as compared to control group. Reduction in wound surface area was significant (p&lt;0.01) in group-II. Maximum gain in thickness of granular tissue was observed in this group. In treatment group 68% patients showed excellent response as compared to 60 % in control group. Ampucare was well tolerated.</span></p><p class="abstracttext"><strong><span lang="EN-IN">Conclusions</span></strong><span lang="EN-IN">: Ampucare treatment markedly accelerates wound healing in patients with bedsore.</span></p> ER -