Diagnostic accuracy of contrast enhanced MRI pelvis in differentiating indeterminate adnexal lesions into benign and malignant with histopathological correlation

Sorath Murtaza, Junaid Iqbal, Saad Ahmed, Ashraf Amir Ali, Marya Hameed, Muhammad Kashif Shazlee


Background: The objective of our study was to determine the diagnostic accuracy of contrast-enhanced magnetic resonance imaging pelvis in differentiating indeterminate adnexal lesions into benign and malignant, while considering histopathological examinations as the gold standard.

Methods: A total 880 patients who underwent contrast enhanced MRI pelvis in our institute from January 2014 to June 2016 were prospectively analyzed.

Results: A total of 880 women were included in this study, of which 782 (88.8%) were younger than 50 years and 98 (11.1%) were older than 50 years. Mean patient age was 56.7 years and mean tumor size was 4.38 cm. There were 648 (73.60%) patients who had a tumor size of >4 cm, and 337 (38.29%) of these tumors were found to be malignant. Furthermore, tumors smaller than 4 cm in size were observed in 232 (26.36%) of patients, of which tumors in 225 (25.56%) patients were benign.

Conclusions: The diagnostic accuracy of contrast-enhanced MRI was found to be significantly high (79.65%) in differentiating indeterminate adnexal lesions into benign and malignant lesions.


Contrast-enhanced MRI, Ovarian tumor, Benign and malignant, Histopathology

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