DOI: http://dx.doi.org/10.18203/2319-2003.ijbcp20210560

Super refractory seizures with autoimmune encephalitis and ventilator associated pneumonia: a case report

A. Priya Shiva, Aswathy M. Shaji, Mohammed Fardan, K. Arun Chander Yadav

Abstract


Autoimmune encephalitis is an immune-mediated syndrome with sub-acute to chronic presentations, such as memory impairment, altered sensorium, behavioral abnormality, psychosis, and seizures. Treatment as such must not be procrastinated due to pending laboratory workup, as early recognition and initiation of therapy prevents long term neurological sequelae. This is a case report of an 11-year-old male who presented with neuropsychiatric symptoms, altered sensorium and high-grade fever which evolved into refractory status epilepticus and autonomic dysfunction. While his MRI had positive findings of encephalitis, he tested negative for infectious diseases and antibody panels.

 


Keywords


Autoimmune encephalitis, Refractory status epilepticus, Autonomic dysfunction, Altered sensorium

Full Text:

PDF

References


Kirmani BF, Barr D, Robinson DM, Pranske Z, Fonkem E, Benge J et al. Management of Autoimmune encephalitis with Super Refractory Status Epilepticus. Front Neurol. 2018;259(9):1-4.

Dubey D, Kalita J, Misra UK. Status epilepticus: Refractory and super-refractory. Neurol India. 2017;65(7):12-7.

Shorvon S, Ferlisi M. A critical review of Available Therapies and a Clinical Treatment Protocol for Super Refractory Seizures. Brain. 2011;134(10):2802-18.

Misra UK, Kalita J, Dubey D. A Study of Super Refractory Status Epilepticus from India. Front Neurol. 2017;636(8):1-6.

Sinha A, Bagga A. Pulse steroid therap. Indian J Pediatr. 2008;75:1057-66.

Newey CR, Mullaguri M, Hantus S, Punia V, George P. Super-Refractory Status Epilepticus Treated with High Dose Perampanel: Case Series and Review of the Literature. Case Rep Cri Care. 2019;1-7.