Paracetamol induced erythema multiforme major: a rare case report

Authors

  • Mukesh Kumar Department of Pharmacology, AIIMS, Patna, Bihar, India
  • . Soni Department of Pharmacology, Manipal Tata Medical College, Jamshedpur, Jharkhand, India

DOI:

https://doi.org/10.18203/2319-2003.ijbcp20210192

Keywords:

Paracetamol, Erythema multiforme, Adverse drug reaction

Abstract

Paracetamol is the most quotidian drug used for fever and pain. Adverse drug reaction to paracetamol in India are rare, at times they can lead to lethal situations like erythema multiforme. The most common drug induced erythema multiforme are due to drugs like barbiturate, NSAIDs, penicillin, sulfonamide, nitrofurantoin, phenothiazines and anticonvulsants. There are very few detailed case reports of erythema multiforme due to use of paracetamol. We report a case of erythema multiforme which occurred due to use of paracetamol. The clinical feature and management of patient are described in brief.

Author Biographies

Mukesh Kumar, Department of Pharmacology, AIIMS, Patna, Bihar, India

Senior resident

Department of Pharmacology

. Soni, Department of Pharmacology, Manipal Tata Medical College, Jamshedpur, Jharkhand, India

Assistant professor

Department of pharmacology

References

Schneider G, Kachroo S, Jones N, Crean S, Rotella P, Avetisyan R et al. A systematic review of validated methods for identifying erythema multiforme major/minor/not otherwise specified, Stevens-Johnson Syndrome, or toxic epidermal necrolysis using administrative and claims data. Pharmacoepidemiology Drug Safety. 2012;21:236-9.

Mamatha K, Ravali TR, Chiranjeevi P, Maheswari E. A Case Report on Ciprofloxacin Induced Erythema Multiforme. SAS Tech-Tech J RUAS. 2015;14(2):45-8.

Stevens DL, Bisno AL, Chambers HF, Dellinger EP, Goldstein EJ, Gorbach SL et al. Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the Infectious Diseases Society of America. Clinical Infectious Diseases. 2014;59(2):e10-52.

Buencamino MC, Goel SS, Tuthill RJ, Taege A. A 19-year-old man with oral ulcers, pulmonary infiltrates, and rash. Cleveland Clinic Journal of Medicine. 2007;74(11):773.

Farthing P, Bagan JV, Scully C. Number IV erythema multiforme. Oral Diseases. 2005;11(5):261-7.

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Published

2021-01-25

How to Cite

Kumar, M., & Soni, . (2021). Paracetamol induced erythema multiforme major: a rare case report. International Journal of Basic & Clinical Pharmacology, 10(2), 198–200. https://doi.org/10.18203/2319-2003.ijbcp20210192

Issue

Section

Case Reports