DOI: http://dx.doi.org/10.18203/2319-2003.ijbcp20205537

Prescribing patterns in the management of arthritis in a rural tertiary care teaching hospital

Neha K., Ravi Shankar M.

Abstract


Background: Based on 2003 National Health Insurance Scheme (NHIS) data, a projected 67 million (25%) adults aged 18 years or older will have arthritis and 25 million (37%) of those will have arthritis-attributable activity limitations by the year 2030. Objective of this study is to know the prevalence of different types of arthritis, current trends of drug prescribing patterns in its management and to create awareness about rational use of drugs in a rural tertiary care hospital.

Methods: This was an observational study of drug prescriptions among 100 arthritis patients in a tertiary care teaching hospital, India. Patients diagnosed with arthritis with or without co-morbidities were enrolled in the study considering the inclusion and exclusion criteria with a verbal informed consent.

Results: Out of 100 arthritis cases, prevalence of Osteoarthritis (OA) was seen more than Rheumatoid arthritis (RA). Osteoarthritis was more commonly seen in males and RA in females. Arthritis was more prevalent in the age group of 36-65 years. Oral route was the most preferred route of administration of drugs and Nonsteroidal anti-inflammatory drugs (NSAIDs) were the first choice. Vitamin D3+ calcium was the most commonly prescribed drug in arthritis. Diclofenac was the most commonly used drug for monotherapy in OA and methotrexate in RA.

Conclusions: In this study, some patients diagnosed with RA were treated with NSAIDs as first line and no Disease Modifying Anti-Rheumatic Drugs (DMARD) were given. This irrational prescribing trend should be changed. Non-pharmacological treatment has a qualitative role in treating arthritis and should be advised instead of multiple drug therapy.


Keywords


Prescribing patterns, Arthritis, Osteoarthritis, Rheumatoid arthritis, Nonsteroidal anti-inflammatory drugs, Disease modifying anti-rheumatic drugs, Vitamin D3+ calcium

Full Text:

PDF

References


Birkett D, Smet PD, Adjei DO, Trolin I, Bergman U, Strom H, et al. Introduction to Drug Utilization Research. WHO. 2003;6-9. Accessed on 11 September 2020.

Shirpa J, Zafar KY, Prerna U, Kumar A. Assessment of Prescribing Pattern in a Private Teaching Hospital in India. International Journal of Pharma Sciences. 2012;3(3):219-22.

Shaikh U, Chandra SN, T J, Shankar J, Kotipalli R. Prescription Trends in department of Orthopaedics at Tertiary Care Teaching Hospital. Journal of Chemical and Pharmaceutical Research. 2013;5(11):512-17.

Hogerzeil HV. Promoting rational prescribing: an international perspective. Br J Clin Pharmacol. 1995;39:1-6.

Uppal R, Nayak P, Sharma PL. Prescribing trends in internal medicine. Int J Clin Pharm Ther Toxicol. 1984;22:373-76.

Shankar PR, Pai R, Dubey AK, Upadhyay DK. Kathmandu university medical journal. 2007;5(17):16-21.

Velentina BP. Pharmacy practice. 2009;7(2):88-93.

A leading cause of disability in the United States. Arthritis: National Academy On An Aging Society. 2000;(5):1-6.

Arthritis: Data and Statistics. CDC. 2015. Available from: http://www.cdc.gov/arthritis/data_statistics/index.html. Accessed on 10 September 2020.

Grijalva GC, Chung PC, Stein. MC, Jr Mitchel. FE, Griffin RM. Changing patterns of medicine use in patients with Rheumatoid arthritis in a Medical population USA. Oxford University Press,. 2008;47:1061-64.

B. Premkumar, Srinivasamurthy M, Rajagopal K. A Retrospective Study on Clinical Characteristics of Rheumatoid Arthritis Patients. Biomedical & Pharmacology Journal. 2013;6(2):471-475.

Ahmed M, Ali N, Rahman ZU, Khan MM. A study on prescribing patterns in the management of arthritis in the department of orthopedics. Der Pharmacia Lettre. 2012;4(1):5-27.

Gurung S, Babu S, Sabu S, Shibu RM, Begum R, Nanjwade BK. A study on prescribing pattern in the management of osteoarthritis and rheumatoid arthritis in the department of orthopaedics. World journal of pharmacy and pharmaceutical sciences. 2016;5(4):1472-93.

Jhanwar P, Pandey S, Sharma N, Jhanwar A. Drug utilization study of osteoarthritis in a tertiary care teaching hospital of rajasthan. International journal of pharmaceutical sciences review and research. 2012;14(2):35‐7.