Rosuvastatin induced gynecomastia: a rare presentation of newer statin

Authors

  • Suman Ruhela Medical Officer, SK Medical College and Hospital, Sikar, Rajasthan, India
  • Manish Ruhela Department of Cardiology, Noble Care Hospital, Sikar, Rajasthan, India
  • Rakesh Kumar Ola Department of Cardiology, Noble Care Hospital, Sikar, Rajasthan, India
  • Mahesh Rao Department of General Surgery, Noble Care Hospital, Sikar, Rajasthan, India

DOI:

https://doi.org/10.18203/2319-2003.ijbcp20204505

Keywords:

Rosuvastatin, Gynecomastia, Naranjo scale

Abstract

Gynecomastia is a common benign disease characterized by the progressive enlargement of the glandular tissue of the male breast. The etiology may vary and may be physiological, pharmacological, pathological, or even idiopathic. Among men, drug induced gynecomastia may account for 10-20% of cases. Several case reports have associated this condition to the use of statins. However, there are few case reports of rosuvastatin induced gynecomastia have been reported in literature. We describe a 45-year-old male who developed bilateral gynecomastia after one month of rosuvastatin therapy, after switching to a different or less potent statin (atorvastatin), his symptoms resolved with-in one month. Use of the Naranjo adverse drug reaction probability scale indicated a possible relationship between the patient’s development of gynecomastia and rosuvastatin therapy.

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Published

2020-10-21

How to Cite

Ruhela, S., Ruhela, M., Ola, R. K., & Rao, M. (2020). Rosuvastatin induced gynecomastia: a rare presentation of newer statin. International Journal of Basic & Clinical Pharmacology, 9(11), 1744–1745. https://doi.org/10.18203/2319-2003.ijbcp20204505

Issue

Section

Case Reports