DOI: http://dx.doi.org/10.18203/2319-2003.ijbcp20204092

Assessment of drug utilization among geriatric patients based on defined daily dose concept in a rural tertiary care teaching hospital

K. Padmavathi, S. A. Arun Raaj, S. Subash, C. K. Dhanapal, S. Periasamy

Abstract


Background: The objectives of the study were to use the anatomical therapeutic chemical classification (ATC) /defined daily dose (DDD) concept to study the drug utilization pattern in geriatric patients in a rural tertiary care teaching hospital.

Methods: An observational study was conducted at Rajah Muthiah Medical College Hospital (OPD and IPD) over a period of six months from November 2018 to April 2019. The data was collected from 204 patients using specially designed data collection form. The patients were selected based on inclusion and exclusion criteria.

Results: A total of 204 patients were included in this study. The study population consisting of males 130 (63.7%) and females 74 (36.2%). Diseases related to the cardiovascular system 67 (32.84%) were the most common cause for the geriatric patients to attend the hospital, followed by surgical diseases 47 (23.03%), Oncological diseases 2 (0.98%) were the least frequency encountered. The average number of drugs prescribed per prescription was 8.79. Out of 1795 drugs prescribed, 60.86% of drugs were prescribed in generic form, and 39.14% were prescribed in brand name. The study analysed that 71.25% of drugs prescribed were from essential drug list (EDL) 2016-2018. Number of prescriptions with an injection was 74.04%. Paracetamol (N02B01) was the most frequently prescribed drug, followed by Amlodipine (C08CA01), Dexamethasone (H02AB02), Clopidogrel (B01AC04), Ferrous sulfate (B03AA07), Acetylsalicylic acid (B01AC06), Hydrocortisone (H02AB09), Tamsulosin (G04CA02), Atorvastatin (C10AA05), Furosemide (C03CA01).

Conclusions: Drug utilization study can help in evaluating the quality of care given to the geriatric patients and promote rational use of medicines.


Keywords


ATC/DDD system, Drug utilization pattern, Geriatric patients

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References


World health organization. Introduction to drug utilization. Available at https://apps.who.int/ medicinedocs/en/d/Js4876e/2.html. Accessed on 17 July 2020.

Dinesh Kumar Meena, M. Jayanthi-Drug utilization research: a review Int J of Basic Clinical Pharmacol. 2019;8(2):354-61.

WHO International Working Group for Drug Statistics Methodology, WHO Collaborating Centre for Drug Statistics Methodology and amp; WHO Collaborating Centre for Drug Utilization Research and Clinical Pharmacological Services. (‎2003)‎. Introduction to drug utilization Research. WHO. https://apps.who.int/iris/handle/10665/42627. Accessed on 17 July 2020.

Starner CI, Gray Sl, Guay DR, Hajjar ER, Handla SM Geriatrics. In: Dipiro ST, Talbert RL, Yee GC, Matzke GR, Wells BG, Posey LM, editors. Pharmacotherapy A pathophysiologic approach 7th edition Newyork: Mc Graw Hill; 2008:57-66.

Shah RB, Gajjar BM, Desai SV. Drug utilization pattern among geriatric patients assessed with the anatomical therapeutic chemical classification/defined daily dose system in a rural tertiary care teaching hospital. Int J Nutr Pharmacol Neurol Dis. 2012;2(3):258-65.

World health organization. DDD indicators. Available at https://www.who.int/medicines/regulation/medicines-safety/toolkit_indicators/en/index1.html. Accessed on 17 July 2020.

World health organization. Prescribing indicators. Available at https://apps.who.int/medicinedocs/en/d/Js2289e/3.1.html. Accessed on 17/8/2020.

National List of Essential Medicines-2015 Central Drugs Standard. Available at: http://www.cdsco.nic.in/National%20 List%20of%20Essential%20Medicine-%20final %20copy. pdf. Accessed on 17 July 2020.

WHO Model Lists of Essential Medicines 2016-2018. Available at: http://www.who.int/medicines/ publications/ essential medicines. Accessed on 17 July 2020.

Association of Physicians of India. Indian guidelines on hypertension (I.G.H.)-III. 2013. J Assoc Physicians India. 2013;61(2):6-36. Available at: https://pubmed.ncbi.nlm.nih.gov/24475694/. Accessed on 17 July 2020.

Nandagopal A, Koneru A, Rahman A, Pasha MD, Ali MKY. Assessment of Rational Drug Prescribing pattern in Geriatric Patients in Hyderabad Metropolitan. Ind J Pharm Pract. 2017;10(3):174-8.

Kolhe A, Kale AS, Padwal SL. Drug utilization study in geriatric patients at rural tertiary care hospital. Asian J Pharm Clin Res. 2015;8(4):90-92.

Nishandar TB, kale AS, Pise HN. Drug utilization pattern in geriatric patients attending outpatient department at rural tertiary care hospital in Maharashtra. Asian J Pharm Clin Res. 2017;10(2):314-6.

Patanaik SK, Pattanayak C, Prasad A, Chauhan AS. Drug utilization pattern in an intensive care unit setting in Eastern India. Int J Basic Clin Pharmacol. 2015;4(6):1136-41.

Patel VJ, Malhotra S, Gautam C. Drug use pattern of antihypertensive drugs in outdoor patients of a teaching hospital. Guj Med J. 2002;59:41-3.

Satoshkar RS, Bhandarkar SD, Rege NN. Pharmacology and Pharmacotherpaeutics. 20th ed. Mumbai: Popular Prakashan Private Limited; 2007:429.