A comparative clinical study on efficacy of terbinafine and griseofulvin in patients with tinea corporis

Authors

  • G. Muthu Kavitha Department of Pharmacology, Government Theni Medical College, Theni, Tamil Nadu, India
  • M. Shanthi Department of Pharmacology, Madurai Medical College, Madurai, Tamil Nadu, India
  • M. S. Ahil Department of Pharmacology, Madurai Medical College, Madurai, Tamil Nadu, India

DOI:

https://doi.org/10.18203/2319-2003.ijbcp20195783

Keywords:

Terbinafine, Griseofulvin, Tinea corporis

Abstract

Background: The objective of the present study was to compare the efficacy of terbinafine and griseofulvin in patients with tinea corporis in a tertiary care hospital, Madurai.

Methods: About 60 patients are selected from the outpatient department of Dermatology according to inclusion and exclusion criteria. They were divided into 2 groups of 30 patients each. Group 1 received tab. terbinafine 250 mg OD and group 2 received 250 mg BD for 4 weeks. All patients were investigated at baseline, end of 2nd week and at end of 4 weeks. Effectiveness of both the drugs were determined by achieving clinical as well as mycological cure. The results were recorded, tabulated and analysed using student’s t test.

Results: Patients in group 1 showed higher clinical and mycological cure rate when compared with group 2.

Conclusions: Oral terbinafine is the effective antifungal agent in the treatment of extensive tinea corporis infection.

References

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Published

2019-12-24

How to Cite

Muthu Kavitha, G., Shanthi, M., & Ahil, M. S. (2019). A comparative clinical study on efficacy of terbinafine and griseofulvin in patients with tinea corporis. International Journal of Basic & Clinical Pharmacology, 9(1), 181–185. https://doi.org/10.18203/2319-2003.ijbcp20195783

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Original Research Articles