A pharmacovigilance study of adverse drug reactions in a tertiary care hospital in Haryana

Authors

  • Manmeet Kaur Department of Pharmacology, Kalpana Chawla Government Medical College, Karnal, Haryana, India
  • Tirthankar Deb Department of Pharmacology, Kalpana Chawla Government Medical College, Karnal, Haryana, India
  • Jayant Kairi Department of Pharmacology, Kalpana Chawla Government Medical College, Karnal, Haryana, India
  • Ankit Arora Department of Pharmacology, Kalpana Chawla Government Medical College, Karnal, Haryana, India

DOI:

https://doi.org/10.18203/2319-2003.ijbcp20194149

Keywords:

Adverse drug reactions, Pharmacovigilance programme of India, Adverse drug reaction monitoring centres, Causality assessment

Abstract

Background: Adverse drug reaction (ADR) is an inevitable risk associated with all the prescribed medicines. They vary in severity & duration in any population. Thus, ADRs are monitored and assessed on a large scale in our country by the Pharmacovigilance programme of India through adverse drug reaction monitoring centres. This study was taken to assess the pattern of ADR reported in a tertiary care hospital in Haryana.

Methods: This study was conducted in the Kalpana Chawla Government Medical College, Karnal, Haryana from January 2018 to June 2019. ADRs were collected from different departments and were analysed according to gender, age, department wise distribution, drugs class involved and ADR that was reported.

Results: A total of 233 ADRs were reported in the above mentioned period. Females were affected more than males, maximum number reported in the age group of 21-60 years. The maximum number of ADRs reported was from Dermatology department. Antimicrobials were the class of drugs that were responsible for the maximum number of ADRs reported. Skin manifestations of various types were the most reported ADRs.

Conclusions: By keeping a careful and timely watch majority of the ADRS can be prevented by early intervention. There is also a need to ensure timely check on the drugs supplied by the various pharmaceutical companies who get the contract for government supply. This will be a step towards improving patient safety.

Author Biographies

Manmeet Kaur, Department of Pharmacology, Kalpana Chawla Government Medical College, Karnal, Haryana, India

Demonstrator
Department of Pharmacology
Kalpana Chawla Govt Medical college, karnal, haryana

Tirthankar Deb, Department of Pharmacology, Kalpana Chawla Government Medical College, Karnal, Haryana, India

Associate Professor
Department of Pharmacology
Kalpana Chawla Govt Medical college

Jayant Kairi, Department of Pharmacology, Kalpana Chawla Government Medical College, Karnal, Haryana, India

Professor & Head

Department of Pharmacology

Kalpana Chawla Govt Medical college, Karnal, Haryana

Ankit Arora, Department of Pharmacology, Kalpana Chawla Government Medical College, Karnal, Haryana, India

Demonstrator
Department of Pharmacology
Kalpana Chawla Govt Medical college, Karnal, Haryana

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Published

2019-09-25

How to Cite

Kaur, M., Deb, T., Kairi, J., & Arora, A. (2019). A pharmacovigilance study of adverse drug reactions in a tertiary care hospital in Haryana. International Journal of Basic & Clinical Pharmacology, 8(10), 2184–2190. https://doi.org/10.18203/2319-2003.ijbcp20194149

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Original Research Articles