Assessment of type, clinical characteristics, nature and outcome of poisoning cases in two hospitals of U.A.E.

Authors

  • Khulood Ebrahim Al-Sharhan Al-Naeimi Department of Clinical Pharmacy and Pharmacology, RAK College of Pharmaceutical Sciences (RAKCOPS), RAK Medical and Health Sciences University (RAKMHSU), Ras Al-Khaimah, UAE
  • Sathvik Belagodu Sridhar Department of Clinical Pharmacy and Pharmacology, RAK College of Pharmaceutical Sciences (RAKCOPS), RAK Medical and Health Sciences University (RAKMHSU), Ras Al-Khaimah, UAE

DOI:

https://doi.org/10.18203/2319-2003.ijbcp20191024

Keywords:

Acute poisoning, Drugs in poisoning, Household chemicals, Snake bite

Abstract

Background: Poisoning is an important public health problem, causing significant morbidity and mortality throughout the world. Currently limited data available in UAE regarding the incidence, type of poison, management and outcome of poisoning cases both in adults and children are very limited. The present study focused to assess the type, clinical characteristics, nature and outcome of poisoning cases in two secondary and Tertiary Care Hospitals of U.A.E.

Methods: This was a prospective observational study conducted in two hospitals of northern emirates of U.A.E. Patient case notes related to hospital admissions due to poisoning were identified and reviewed by the study investigator. Various details such as patient demographic characteristics, type, clinical characteristics, management and outcome of poisoning were entered into a suitably designed data collection form. The collected data were analyzed using poison severity and snakebite severity assessment scales.

Results: A total of 97 poisoning cases was identified during the study period. The prevalence of poisoning among male (50.5%) and female (49.5%) was found to be almost similar. The majority of poisoning cases 55 (56.7%) was of accidental type. The most common type of agent responsible for poisoning was drugs 61 (62.9%). Paracetamol was the most common drug involved in poisoning 16 (26.2%). The outcome of the poisoning was a recovery in majority 96 (98.9%) of the cases. Demographic factors such as gender, age, nationality and occupation were found to be significantly (p<0.05) associated with the intention and type of poisoning agent.

Conclusions: The study concluded that the most common poisoning agent involved in poisoning was drugs. The majority of the poisoning cases were of accidental type. The outcome of the poisoning was a recovery in the majority of the cases and no mortality were reported.

References

Peter A. Chtka. Clinical toxicology. Joseph T. Dipiro, eds. Pharmacotherapy: a pathophysiologic approach. 8th ed. McGraw-Hill: USA; 2008: 27-36.

Maharani B, Vijayakumari N. Profile of poisoning cases in a Tertiary care Hospital, Tamil Nadu, India. J Applied Pharmaceutical Sci. 2013;3(1):91.

Zaheer MS, Aslam M, Gupta V, Sharma V, Khan SA. Profile of poisoning cases at a North Indian tertiary care hospital. Heal Population Perspective Issues. 2009;32(4):176-83.

National capital poison Center. Poisoning the local picture. Available at: http://www.poison.org/stats/#Poisonings:_The_National_Picture. Accessed on October 7, 2018.

Hawkins LC, Edwards JN, Dargan PI. Impact of restricting paracetamol pack sizes on paracetamol poisoning in the United Kingdom. Drug safety. 2007;30(6):465-79.

Office for national statistics. Death related to Drug poisoning in England and Wales, 2012. Accessed from: http://www.ons.gov.uk/ons/rel/subnational-health3/deaths-related-to-drug-poisoning/2012/stb---deaths-related-to-drug-poisoning-2012.html. Accessed 15 September 2013.

Daly FF, Fountain JS, Murray L, Graudins A, Buckley NA. Guidelines for the management of paracetamol poisoning in Australia and New Zealand-explanation and elaboration. Med J Aus. 2008;188(5):296.

Rajasuriar R, Awang R, Hashim SBH, Rahmat HRBH. Profile of poisoning admissions in Malaysia. Human & Experimental Toxicology. 2007;26(2):73-81.

Ramanath KV. Kumar NHD. Study the assessment of poisoning cases in a rural tertiary care teaching hospital by a clinical pharmacist. Asian J Pharmaceutical Clin Res. 2012;5(2):138-41.

Khajuria VI, Shah SA, Tandon VR, Gillani ZA, Gupta RO, Sharma AM, et al. Organophosphorus poisoning in a tertiary hospital of north India-a preliminary report. Bull Pharmaceutical Med Sci (BOPAMS). 2013;1(1):41-3.

Veale DJ, Wium CA, Müller GJ. Toxicovigilance II: A survey of the spectrum of acute poisoning and current practices in the initial management of poisoning cases admitted to South African hospitals. SAMJ. 2013;103(5):298-303.

Hanssens Y, Deleu D, Taqi A. Etiologic and demographic characteristics of poisoning: a prospective hospital-based study in Oman. J Toxicol Clin Toxicol. 2001;39(4):371-80.

Lall SB, Al Wahaibi SS, Al Riyami MM, Al Kharusi K. Profile of acute poisoning cases presenting to health centres and hospitals in Oman. East Mediterr Health J. 2003; 9 (5-6): 944-54.

Moazzam M, Al-Saigul AM, Naguib M, Al Alfi MA. Pattern of acute poisoning in AL-Qassim region: a surveillance report from Saudi Arabia, 1999-2003. East Med Heal J. 2009;15(4):1005-10.

Dawson KP, Harron D, Mcgrath L, Amirlak I, Yassin A. Accidental poisoning of children in the United Arab Emirates. East Med Heal J. 1997;3(1):38-42.

Health statistics 2016. Available at: https://www.haad.ae/HAAD/LinkClick.aspx?fileticket=FBdPFZYpdCc%3d&tabid=1516. Accessed on October 7, 2018.

Persson HE, Sjöberg GK, Haines JA, de Garbino JP. Poisoning severity score. Grading of acute poisoning. J Toxicol Clin Toxicol. 1998;36(3):205-13.

Spiller HA, Bosse GM. Prospective study of morbidity associated with snakebite envenomation. J Toxicol Clin Toxicol. 2003;41(2):125-30.

Camidge DR, Wood RJ, Bateman DN. The epidemiology of self‐poisoning in the UK. Brit J Clin Pharmacol. 2003;56(6):613-9.

Albuquerque PL, Silva Junior GB, Jacinto CN, Lima CB, Lima JB, Veras MD, Daher EF. Epidemiological profile of snakebite accidents in a metropolitan area of northeast Brazil. Rev Inst Med Trop Paulo. 2013;55(5):347-51.

Howlader MA, Sardar MH, Amin MR, Morshed MG, Islam MS, Uddin MZ, et al. Clinico-epidemiological pattern of poisoning in a tertiary level hospital. J Dhaka Med Coll. 2008;17(2):111-5.

Paudyal BP. Poisoning: pattern and profile of admitted cases in a hospital in central Nepal. JNMA. 2005;44(159):92-6.

Liu Q, Zhou L, Zheng N, Zhuo L, Liu Y, Liu L. Poisoning deaths in China: type and prevalence detected at the Tongji Forensic Medical Center in Hubei. Forensic Sci Inter. 2009;193(1-3):88-94.

Sulastri S, Nur Afni A, Zyoud SH, Abdullah AA, Rahmat A. Cases of accidental hydrocarbon ingestion referred to the Malaysian national poisoning center. JMT. 2012;8:192.

Peden M, Oyegbite K, Ozanne-Smith J, Hyder AA, Branche C, Rahman AK. Poisoning. In: World Report on Child Injury Prevention. Geneva, Switzerland: World Health Organization; 2008:142-162.

Khadka SB, Ale SB. A study of poisoning cases in emergency Kathmandu Medical College Teaching Hospital. KUMJ. 2005;3(4):388-91.

Prajapati T, Prajapati K, Tandon R, Merchant S. Acute chemical and pharmaceutical poisoning cases treated in civil hospital, Ahmedabad: one-year study. Asia Pacific J Med Toxicol. 2013;2(2):63-7.

Karki RK, Risal A. Study of Poisoning Cases in a Tertiary Care Hospital. Kathmandu Uni Med J. 2012;10(4):70-3.

Lifshitz M and Gavrilov V. Deliberate Self-Poisoning in Adolescents. IMAJ. 2002;14:252-4.

Ramesha KN, Rao KB, Kumar GS. Pattern and outcome of acute poisoning cases in a tertiary care hospital in Karnataka, India. Ind J Crit Care Med Peer-reviewed Official Pub Ind Soc Crit Care Med. 2009;13(3):152.

Fathelrahman AI, Ab Rahman AF, Mohd Zain Z. MS 04-044: demographic features of drug and chemical poisoning in northern Malaysia. Clin Toxicol. 2005;43(2):89-94.

Veale DJ, Wium CA, Müller GJ. Toxicovigilance I: a survey of acute poisonings in south africa based on Tygerberg poison information centre data. South Afr Med J. 2013;103(5):293-7.

Adnan LH, Kamaldin J, Mohamad N, Salatore SA, Suhaimi R, Zainuddin ND. The risk of accidental chemical poisoning cases among children (≤ 12 Years Old) admitted to Hospital University Sains Malaysia: 5 Years Review. J Clin Toxicol. 2013;3(5):177.

Al-Moamary MS, Al-Shammary AS, Al-Shimemeri AA, Ali MM, Al-Jahdali HH, Awada AA. Complications of carbon monoxide poisoning. Saudi Med J. 2000;21(4):361-3.

Patil A, Peddawad R, Verma VC, Gandhi H. Profile of acute poisoning cases treated in a tertiary care hospital: a study in Navi Mumbai. Asia Pac J Med Toxicol. 2014;3(1):36-40.

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Published

2019-03-23

How to Cite

Al-Naeimi, K. E. A.-S., & Sridhar, S. B. (2019). Assessment of type, clinical characteristics, nature and outcome of poisoning cases in two hospitals of U.A.E. International Journal of Basic & Clinical Pharmacology, 8(4), 622–628. https://doi.org/10.18203/2319-2003.ijbcp20191024

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Section

Original Research Articles