DOI: http://dx.doi.org/10.18203/2319-2003.ijbcp20190533

Can these older drugs bring new hope in Rheumatoid arthritis?

Babu L. N.

Abstract


.

Full Text:

PDF

References


Friedman B, Cronstein B. Methotrexate mechanism in treatment of rheumatoid arthritis. Jt Bone Spine Rev Rhum. 2018 Aug 3.

Allegra CJ, Drake JC, Jolivet J, Chabner BA. Inhibition of phosphoribosylaminoimidazolecarboxamide transformylase by methotrexate and dihydrofolic acid polyglutamates. Proc Natl Acad Sci U S A. 1985 Aug;82(15):4881-5.

Baggott JE, Vaughn WH, Hudson BB. Inhibition of 5-aminoimidazole-4-carboxamide ribotide transformylase, adenosine deaminase and 5’-adenylate deaminase by polyglutamates of methotrexate and oxidized folates and by 5-aminoimidazole-4-carboxamide riboside and ribotide. Biochem J. 1986 May 15;236(1):193-200.

Aminophylline for methotrexate-induced neurotoxicity. - PubMed - NCBI [Internet]. 2018 [cited 2018 Dec 22]. Available at: https://www.ncbi.nlm.nih.gov/pubmed/7776773

Cronstein BN, Eberle MA, Gruber HE, Levin RI. Methotrexate inhibits neutrophil function by stimulating adenosine release from connective tissue cells. Proc Natl Acad Sci USA. 1991 Mar 15;88(6):2441-5.

Cronstein BN, Kramer SB, Weissmann G, Hirschhorn R. Adenosine: a physiological modulator of superoxide anion generation by human neutrophils. J Exp Med. 1983 Oct 1;158(4):1160-77.

Differential regulatory effects of adenosine on cytokine release by activated human monocytes. - PubMed - NCBI [Internet]. 2018 [cited 2018 Dec 22]. Available at: https://www.ncbi.nlm.nih.gov/pubmed/?term=Differential+regulatory+effects+of+adenosine+on+cytokine+release+by+activated+human+monocytes.

Sajjadi FG, Takabayashi K, Foster AC, Domingo RC, Firestein GS. Inhibition of TNF-alpha expression by adenosine: role of A3 adenosine receptors. J Immunol Baltim Md 1950. 1996 May 1;156(9):3435-42.

Adenosine enhances IL-10 secretion by human monocytes. - PubMed - NCBI [Internet]. 2018 [cited 2018 Dec 22]. Available at: https://www.ncbi.nlm.nih.gov/pubmed/8666814

Balakumar P, Nyo YH, Renushia R, Raaginey D, Oh AN, Varatharajan R, et al. Classical and pleiotropic actions of dipyridamole: Not enough light to illuminate the dark tunnel? Pharmacol Res. 2014 Sep;87:144-50.

Ciacciarelli M, Zerbinati C, Violi F, Iuliano L. Dipyridamole: a drug with unrecognized antioxidant activity. Curr Top Med Chem. 2015;15(9):822-9.

Gamboa A, Abraham R, Diedrich A, Shibao C, Paranjape SY, Farley G, et al. Role of adenosine and nitric oxide on the mechanisms of action of dipyridamole. Stroke. 2005 Oct;36(10):2170-5.