A study to assess the therapeutic role of GM-CSF (EMGRAST -M) on augmentation of total leucocyte count and total platelet count in cancer patients after chemotherapy

Authors

  • Amit Kumar Department of Medical Oncology, Brahmanand Narayan Hrudyalay, Jamshedpur, Jharkhand Province, India
  • Kusum Kumari Department of Pharmacology and Therapeutics, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand Province, India
  • Priyanki . Department of Pharmacology and Therapeutics, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand Province, India
  • Pranay Kumar Mishra Department of Surgery, Tinplate Hospital, Jamshedpur, Jharkhand, Province, India

DOI:

https://doi.org/10.18203/2319-2003.ijbcp20183493

Keywords:

Chemotherapy, GM-CSF, Total leucocyte count, Total platelet count

Abstract

Background: The aim of the present study was to assess the therapeutic role of GM-CSF (EMGRAST -M) on augmentation of total leucocyte count and total platelet count in cancer patients after chemotherapy.

Methods: The total leucocyte count (TLC) and total platelet count (TPC) of thirty patients on chemotherapy were obtained before and after the administration of GM-CSF. The results were analysed retrospectively for the effect of GM-CSF on these parameters. Statistical analysis was done, and graphs were made by Libre office calc and Student’s T Test was used for comparison of data.

Results: The study showed that EMGRAST-M had an impressive effect on both the platelet count and the leucocyte count.

Conclusions: GM-CSF has a great therapeutic role in the enhancement of platelet count and leucocyte count in patients of cancer chemotherapy.

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Published

2018-08-23

How to Cite

Kumar, A., Kumari, K., ., P., & Mishra, P. K. (2018). A study to assess the therapeutic role of GM-CSF (EMGRAST -M) on augmentation of total leucocyte count and total platelet count in cancer patients after chemotherapy. International Journal of Basic & Clinical Pharmacology, 7(9), 1803–1807. https://doi.org/10.18203/2319-2003.ijbcp20183493

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Original Research Articles