Analgesic prescribing trends in musculoskeletal disorders

Authors

  • Siddiqui R. A. Department of Pharmacology, NKPSIMS, Nagpur, Maharashtra, India
  • Shende T. R. Department of Pharmacology, NKPSIMS, Nagpur, Maharashtra, India
  • Shreya Shekhar Department of Pharmacology, NKPSIMS, Nagpur, Maharashtra, India

DOI:

https://doi.org/10.18203/2319-2003.ijbcp20183489

Keywords:

Fixed dose combination, Non-steroidal anti-inflammatory drugs, Over-the-counter

Abstract

Background: Musculoskeletal disorders like osteoarthritis, rheumatoid arthritis, bursitis, backache, tendinitis, cervical spondylitis etc. are very commonly encountered in orthopaedic practice and are generally treated with various analgesic drugs. There are number of non-steroidal anti-inflammatory drugs (NSAIDs), opiod analgesics and also fixed dose combination (FDC) of analgesics available for the treatment of such disorders with some advantages and disadvantages of these drugs. Since few studies are there on utilization of analgesic drugs in the orthopaedic practice, this study was undertaken to determine the current prescribing trends for these disorders.

Methods: It was record based observational study carried out at NKP salve institute of medical sciences, Nagpur. A total of 200 prescriptions of patients reported to orthopaedic outpatient department, with presenting complaints of musculoskeletal disorder and rheumatological conditions like osteoarthritis, rheumatoid arthritis, bursitis, backache, tendinitis, cervical spondylitis etc. were noted for the various analgesic drugs prescribed for these disorders.

Results: The common age groups encountered for musculoskeletal disorders were between 41-50 years (26%) and 31-40 years (20%) followed by other age groups. The common conditions for which patient attended orthopaedic outpatient department were low backpain in 42 (21%) and osteoarthritis in 41(20.5%) patients followed by others. Aceclofenac and diclofenac were the most commonly prescribed analgesics in 25 (12.5%) and18 (9%) patients followed by other analgesics. Fixed dose combinations of NSAIDS with other NSAIDS or opoid analgesic were also commonly prescribed. Diclofenac + Paracetamol and Tramadol + Paracetamol were most commonly prescribed combinations in 30 (15%) and 19 (9.5%) patients respectively.

Conclusions: As monotherapy aceclofenac and diclofenac were the most commonly prescribed NSAIDS for various musculoskeletal disorders. Also, fixed dose combinations of NSAIDS with other NSAIDS or opoid analgesic were also commonly prescribed. Diclofenac + Paracetamol and Tramadol + Paracetamol were the most commonly prescribed FDCs in our study.

References

Jyothi R, Pallavi D, Pundarikaksha HP, Sridharmurthy JN, Girish K. A study of prescribing pattern of nonsteroidal anti-inflammatory drugs in orthopedic opd at a tertiary care hospital. Nat J Basic Med Sci. 2013;4(1):71-4.

Qoul KZ, Thuheerat IN, Ashor NA, Hakuz NM. Prescribing patterns of non-steroidal anti-inflammatory drugs in outpatient clinics at royal rehabilitation center in king hussein medical center. Zagazig Uni Med J. 2015 Mar 13;20(5).

Mudhaliar MR, Neeruganti S, Yiragamreddy PR, Mude A. Prescribing patterns of non steroidal anti inflammatory drugs (NSAIDs) in out patient department of an orthopedic specialty hospital. J Global Trends Pharm Sci. 2016;7(3):3296-301.

Singh V, Yadav P, Deolekar P. Current trends of prescribing patterns of NSAIDs in an orthopaedic OPD in a teaching hospital. Int J Pharm Bio Sci. 2014 April;5(2):486-91.

Bhaskar R, Veena DR, Padma L, Kumar PA, Moosaraza S. Prescription pattern of analgesics in orthopedics outpatient department at a tertiary care hospital. Int J Basic Clin Pharmacol. 2017 Jan 21;4(2):250-3.

Latha RA, Srinivasu K, Naik MAB, Reddy JC. A study of prescribing pattern of non- steroidal anti inflammatory drugs in orthopedic outpatient department at a tertiary care hospital. J Evol Med Dental Sci. 2015;4(4):559-64.

Agrawal P, Agrawal VK. Evaluation of analgesics use in orthopedic department at tertiary care hospital in Bareilly, Uttar Pradesh, India. Int J Basic Clin Pharmacol. 2018 Jan 20;5(6):2538-41.

Alama N, Bhardwaj A, Tiwari R, Sharma S, Dabas V. Drug utilization pattern of patients using NSAIDS in south Delhi hospital. Int J Pharm Pharm Sci. 2012;4(Suppl 3):703-7.

Dalai CK, Kumar A, Banerjee S. Pattern of drugs use in orthopaedic outpatient department in a tertiary care teaching hospital in West Bengal. Indian J Basic Applied Med Res. 2017 December;7(1):238-43.

Nagla A, Wadagbalkar P, Raipurkar S, Patel P. Prescription pattern study of drugs in Orthopedics Outpatient department (OPD) of a Rural Medical College Hospital and Research centre in MP. Indian J Orthopaed Surg. 2016;2(4):367-71.

Tripathi KD. Essentials of medical Pharmacology. Seventh edition, New Delhi Jaypee brothers medical publishers Pvt. Ltd. 2013;204.

Brunton LL, Chabner BA, Knollman BC. Goodman and Gilman’s The Pharmacological Basis of Therapeutics. 12th Edition. New York: McGraw-Hill Companies Inc. 2011;501,508,992.

Nazrina S, Khan MN, Maruf AA. Prescription of analgesics in orthopaedic outpatient department at a tertiary health care facility. Mediscope. 2017 Oct 22;4(1):11-7.

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Published

2018-08-23

How to Cite

A., S. R., R., S. T., & Shekhar, S. (2018). Analgesic prescribing trends in musculoskeletal disorders. International Journal of Basic & Clinical Pharmacology, 7(9), 1782–1786. https://doi.org/10.18203/2319-2003.ijbcp20183489

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Original Research Articles