Drug utilization study in ophthalmology in OPD patients at a tertiary care teaching hospital

Jigar H. Bhatt, Shashwat Verma, Srushti Bagde, Rohit M. Sane, Savita Shahani


Background: Drug therapy is a major component of patient care management in health care settings. Irrational and inappropriate use of drugs in health care system observed globally is being a major concern. In the field of ophthalmology, there have been many drug developments and different classes of drugs with combinational products are available in ophthalmology for the treatment of ophthalmic diseases. Periodic prescription analysis in the form of drug utilization study can improve the quality of prescription and curb the menace of irrational prescribing. Aim and objectives were to study the prescribing pattern and drug utilization trends in Ophthalmology outpatient department at a tertiary care hospital in Navi Mumbai.

Methods: A cross-sectional, observational study was conducted over a period of six months in Ophthalmology department of a tertiary care teaching hospital, Navi-Mumbai. A total of 103 adult patients visiting Ophthalmology OPD for curative symptoms were included and their prescriptions were analyzed with WHO prescribing indicators and additional indices.

Results: Analysis showed that the average number of drugs per prescription was 1.9. Percentage of drugs prescribed by brand was 100 % versus generic 0 %. Percentage of drugs prescribed from National Essential drug list (NEDL) was 53%. The percentage of encounters with antibiotics was 30.6%. The commonest prescribed drugs were ocular lubricants followed by antibiotics. Eye drops were the commonest prescribed dosage form.

Conclusions: Ocular lubricants and antibiotics dominated the prescribing pattern in this study with restraint on polypharmacy, but showed ample scope for improvement in encouraging the ophthalmologist to prescribe generic and selection of essential drugs.


Drug utilization, Ophthalmology, Prescribing pattern, WHO indicators

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World Health Organization (WHO) and International Network for Rational Use of Drugs. How to Investigate Drug Use in Health Facilities: Selected Drug Use indicators. Geneva, Switzerland: WHO; 1993.

Dukes MNG. Drug utilization studies: methods and uses. World Health Organization Regional Publications. European series; 45. Copenhagen, Denmark. Available at:

World Health Organization. Introduction to Drug Utilization Research. Oslo, Norway: WHO; 2003. Available at:

Lee D, Bergman U. Studies of drug utilization. In: Storm LB, editor. Pharmacoepidemiology. Chichester, UK: John Wiley and Sons; 2005:401-417.

Rubin RJ, Altman WM, Mendelson DN. Health care expenditures for people with diabetes mellitus, 1992. J Clin Endocrinol Metab. 1994;78(4):809A-809F.

Jadhav PR, Moghe VV, Deshmukh YA. Drug Utilization Study in Ophthalmology Outpatients at a Tertiary Care Teaching Hospital. ISRN Pharmacology. 2013:768-792.

Biswas NR, Jindal S, Siddiquei MM, Maini R. Patterns of prescription and drug use in ophthalmology in a Tertiary Hospital in Delhi. Br J Clin Pharmacol. 2001;51:267-9.

Maniyar Y, Bhixavatimath P, Akkone V. A drug utilization study in the ophthalmology department of a Medical College, Karnataka, India. J Clin Diagn Res. 2011;5:82-4.

Nehru M, Kohli K, Kapoor B, Sadhotra P, Chopra V, Sharma R. Drug utilization study in outpatient ophthalmology department of Government Medical College. JK Science. 2005;7:149-51.

Sood AK, Gupta A, Dabral T. Indiscriminate use of topical antibiotics: a menace. Indian Journal of Ophthalmology. 1999;47(2):121-24.

Gaynes BI, Fiscella R. Topical nonsteroidal anti-inflammatory drugs for ophthalmic use: a safety review. Drug Safety. 2002;25(4):233-50.

Banerjee I, Bhadury T, Sengupta T, Roy D. Drug Utilization Study in Ophthalmology Out-patient Department of a Medical College in India. Annals of Medical and Health Sciences Research. 2014;4(4):667-70.

Biswas NR, Biswas RS, Pal PS, Jain SK, Malhotra SP, Gupta AS, et al. Patterns of prescriptions and drug use in two tertiary hospitals in Delhi. Indian Journal of Physiology and Pharmacology. 2000 Jan 5;44(1):109-12.

National List of Essential Medicines of India. Ministry of Health and Family Welfare, Government of India; 2015. Available at: