DOI: http://dx.doi.org/10.18203/2319-2003.ijbcp20172245

A critical evaluation of information in drug promotional brochures for validity as per WHO criteria

Navyug R. Singh, Gurpreet K. Randhawa, Resham Kashyap, Gobindnoor Kaur

Abstract


Background: Promotion of drugs through publication of promotional literature is a standard practice of pharmaceutical companies. This study is aimed at critically analyzing the drug promotional brochures.

Methods: Observational study was conducted in Department of Pharmacology, Government Medical College Amritsar according to WHO guidelines. 100 brochures of different pharmaceutical companies were collected at random from various OPDs of a tertiary care hospital.

Results: Only 14 % of total brochures demonstrated overall adherence to WHO guidelines. Safety information was lacking in 88%. Irrelevant pictures were found in 66% brochures while relevant illustrated information was included in only 23 % of brochures. Out of total illustrations found relevant (n=44), 45.5% did not quote any reference, and results didn’t match with original study in 11.4%.

Conclusions: Our study points towards big lacuna in drug promotional brochures, an important source of drug information. Low percentage of adherence to the guidelines in the study reflects commercial interest of pharmaceutical companies and lack of will to correctly disseminate the drug related information.


Keywords


Chart junks, Drug Controller General of India, Drug promotional literature, Data density index, Lie factor

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References


Mali SN, Dudhgaonka S, Bachewar NP. Evaluation of rationality of promotional drug literature using World Health Organization guidelines. Ind J Pharmacol. Oct 2010;42(5):267-72.

Levy R. The role and value of Pharmaceutical Marketing. Arch Fam Med. 1994;3:327-32.

Wind Y. Pharmaceutical advertising. A business school perspective. Arch Fam Med. 1994;3:321-3.

Lexchin J. Physicians and drug companies interact. Can Fam Physician. 1993;39:1881-2.

Charan J, Yadav P, Saxena D, Kantharia ND. Drug advertisements published in Indian Medical Journals: Are they ethical? J Pharm Bioallied Sci. 2011 Jul-Sep;3(3):403-6.

WHO, 1988. Ethical Criteria for medicinal drug Promotion. Available from: http://apps.who.int/medicinedocs/documents/whozip08e/whozip08e.pdf.

Organization of Pharmaceutical Producers of India. OPPI code of pharmaceutical marketing practices 2012. Available from: https://www.indiaoppi.com/sites/default/files/PDF%20files/OPPI%20Code%20of%20Pharmaceutical%20Practices%20%20-%202012_0.pdf

Gitanjali B, Shashindran CH, Tripathi KD, Sethuraman KR. Are drug advertisements in Indian edition BMJ unethical? Br Med J. 1997;315:459-60.

Ved JK, Jagtiani SS, Chitnis KA. Pharmaceutical Advertisements in Indian Scientific Journals: Analysis of Completeness of Information Content. Intern J Pharma Sci Res. 2010;1(9):366-70.

Cardarelli R, Licciardone JC, Taylor LG. A cross-sectional evidence-based review of pharmaceutical promotional marketing brochures and their underlying studies: Is what they tell us important and true? BMC Fam Prac. 2006;7:13.

Cooper RJ, Schringer DL, Wallace RC, Mikulich VJ, Wilkes MS. The quality and quantity of scientific graphs in pharmaceutical advertisements. J Gen Intern Med. 2003;18:294-7.

Tufte ER. The visual display of quantitative information: Graphical Integrity. Cheshire, CT: Graphic press; 1983.

Cooper RJ, Schriger DL, Tashman DA. An evaluation of the graphical literacy of Annals of Emergency Medicine. Ann Emerg Med. January 2001;37:13-9.

Approved Drug Products with Therapeutic Equivalence Evaluations. U.S. Department of Health And Human Services, Food And Drug Administration. Available from: http://www.fda.gov/downloads/Drugs/DevelopmentApprovalProcess/UCM071436.pdf

List of drugs approved. Central Drugs Standard Control Organization of India. Available from: http://cdsco.nic.in/writereaddata/Drugs-approved-list-dec-2015.pdf

Carandang ED, Moulds RF. Pharmaceutical Advertisements in Australian Medical Publications - Have They Improved. Med J Aust. 1994;161:671-2.

Chirac P, Pikon A, Poinsignon Y, Vitry A. Drug Marketing in French-Speaking African Countries. Soc Sci Med. 1993;36:1541-3.

Vlassov V, Mansfield P, Lexchin J, Vlassova A. Do drug advertisements in Russian medical journals provide essential information for safe prescribing? West J Med. 2001;174:391-4.

Al-Aqeel SA, Al-Sabhan JF, Sultan NY. Analysis of written advertising material distributed through community pharmacies in Riyadh, Saudi Arabia. Pharm Pract. 2013 Jul-Sep;11(3):138-43.

Shetty VV, Karve AV. Promotional literature: How do we critically appraise? J Post Grad Med. 2008;54(3):217-25.

Forrow L, Taylor WC, Arnold RM. Absolutely relative: how research results are summarized can affect treatment decisions. Am J Med. 1992;92:1214.

Naylor CD, Chen E, Strauss B. Measured enthusiasm: does the method of reporting trial results alter perceptions of therapeutic effectiveness? Ann Intern Med. 1992;117:916-21.

Interdisciplinary modeling and visualization. Tufte’s design principles. Available from: http://vis.cs.pitt.edu/teaching/cs2620/lectures/L04_Tufte Design.pdf