DOI: http://dx.doi.org/10.18203/2319-2003.ijbcp20164764

Prescription pattern and rationality of drugs study of patients of OPD (outpatient) of orthopedics Department of RKDF Medical College Hospital and Research Centre, Bhopal, MP, India

Rajeev Dalela, Prashant Wadagbalkar, Hareshwar Kumar Mali, Swati Raipurkar

Abstract


Background: To study the prescription pattern of drugs prescribed to patients of OPD of orthopedics department and to analyze the rationality of drugs prescribed by doctors of RKDF MCHRC, Bhopal, MP, India.

Methods: A prospective, observational study was planned for 200 patients selected in the year 2015. Collected data were entered in a predesigned forms downloaded from WHO website. Rationality of drugs prescription was analyzed using WHO drug utilization and prescription indicators. For generic drugs reference NLEM 2011 and for cost analysis, Drug Today 2014 was used.

Results: out of 200 patients, 41%were male and 59% were female. Average numbers of drugs prescribed per prescription was 3.3. Most commonly prescribed drug was Analgesics an Anti-inflammatory (37.1%) in oral as well as Intramuscular injections and Topical forms, Gastric acid inhibitors (15.4%), Muscle relaxants (12.1%) Calcium and Vitamin D, glucosamines (12.1%), Antimicrobials (8%), Steroids (1.8%), Enzyms serratiopeptidase (1.8%). Most commonly prescribed Analegsic was FDC of Trypsin+ Rutoside+ Bromelin+ Diclofenac (30.6%) followed by FDC Acceclofenac+ Paracetamol+ Seratiopeptidase (15.9%), followed by FDC Tramaodol+ Paracetamol (11%).

Drugs prescribed in generic form were 0%.Average cost of treatment was INR 600 per prescription. Most common route of drug prescription was 1. Oral route 81.7%. 2. Topical 6.4%. 3. Injectable intramuscular 6.2% and intra articular 5.7%. Duration of treatment was prescribed in 81%. Frequency of drug administration was mentioned in 100% of prescriptions. EDL prescription was 81%. FDCs were 35%.

Conclusions: There was Poly pharmacy. Drugs prescribed in generic form were very low. Drugs prescribed from NLEM were 81%. CMEs on Rational drug therapy to doctors working in orthopedics department should be conducted to promote rational use.


Keywords


Essential drug list, Generic, Indian drug review, Rational, WHO prescription indicators

Full Text:

PDF

References


WHO. How to investigate drugs use in health facilities: selected drug use indicators, Geneva, World Health Organization, WHO/ DAP/93 1993;1:1-87.

Kaur S, Rajgopalan S, Kaur N, Shafiq N, Bhalla A, Pandhi P, et al. Drug utilization study in medical emergency unit of a tertiary care hospital in North India.Emerg Med Int. 2014;973578.

Ramgopal. Prescription auditing and drug utilization pattern in a tertiary care teaching hospital of western UP. Int J Basic Clin Pharmacol. 2012;1(3):184-90.

Srividya BP, Shashikumar NS, Amardeep G. Retrospective audit of prescription of drugs among inpatients of orthopedic wards at Medical College Teaching Hospital, Mandya. Natl J Physiol Pharm Pharmacol. 2016;6:282-5.

Bithi. Drug Utilization study in orthopedic units, Dhaka, Bangladesh, International current pharm journal. 2014,3(9):315-21.

Ubedulla S, Sekhar NC, Jayasree T, Shankar J, Rohit K. Prescription trends in department of orthopedics at tertiary care teaching hospital. J Chem Pharm Res. 2013;5(11):512-7.

Ingle P, Patil P, Lathi V. Study of rational prescribing and dispensing of prescriptions with NSAIDs in orthopedic OPD. AJPCR. 2015;8(4).

Muraraiah S, Rajarathna K, Vishwanath M, Ramaswamy A, Kamath S, Seshu S, et al. Evaluation of WHO prescribing indicators among orthopaedic inpatients at a tertiary care hospital J Chem Pharm Res. 2014;6(8):278-80.

Elsy MI, Ajitha KN, Sanalkumar KB, Jyothish K, Kuttichira P. Prescribing pattern of analgesics in orthopaedic department of an Indian tertiary care teaching hospital in Kerala. Kerala Med J. 2011;4:149-520.

Choudhary DK, Bezbaruah BK. Prescription pattern of analgesics in orthopedic in patient department at tertiary care hospital in Guwahati ,Northeast India,Indian J Pharmacol. 2016;48:377-81.

Kumar A, Dalai CK, Ghosh AK, Ray M. Drug utilization study of coadministration of nonsteroidal anti-inflammatory drugs and gastroprotective agents in an orthopaedics outpatients department of a tertiary care hospital in West Bengal. Int J Basic Clin Pharmacol. 2013;2(2):199-202.

Shankar PR, Pai R, Dubey AK, Upadhyay DK. Prescribing patterns in the orthopaedics outpatient department in a teaching hospital in Pokhara, western Nepal. Kathmandu Univ Med J. 2007;5(1):16-21.

Patel V, Vaidya R, Naik D, Borker P. Irrational drug use in India: a prescription survey from Goa. J Postgrad Med. 2005;51(1):9-12.

World Health Organization. International Network for Rational Use of Drugs and World Health Organization. How to Investigate Drug Use in Health Facilities: Selected Drug Use Indicators 1993. EDM Research Series No. 7 1993;192.

Afsan M, Haque MME, Alam MM, Noor N. Audit of prescribing practices to evaluate rational use of medicines in the OPD of orthopaedics in a private medical college hospital. J Shaheed Suhrawardy Med Coll. 2012;4(2):39-42.

Thawani V. Rational use of medicines: achievements and challenges. Indian J Pharmacol. 2010;42:63.