A surveillance study of antibiotic use in Pondicherry- 2012

Revathysaravanan ., G.L. Arun Muthukumar

Abstract


Background: An alarming increase in antibiotic use and antimicrobial resistance especially in India is reported by WHO based on the reports from 5 pilot projects. As WHO and GARP India Working GroupState have stressed the importance ofrepeated co-ordinate surveillance to monitor, this study is undertaken in Pondicherry with the objectives of identifying  Commonly used antibiotics, the most exposed age group in Pondicherry and the determining factors for inappropriate use of antibiotics among professionals and community.

Methods: A surveillance study was done by using convenient sampling technique on 50 physicians and 100 people in community in the form of questionnaires after getting informed consent. The role of pharmacy was not includeddue to possible non reliability. The results are expressed by analyzing the data using descriptive statistics.

Results: Experience and cost had been the main deciding factors for choosing the antibiotic for prescription. Third generation Cephalosporin was more prescribed and adults were exposed more to antibiotics with 81.56% and 75% from urban and   rural respectively. Self medication was practiced by 14 out of 100 participants and more than 75% were not aware about proper use of antibiotics.

Conclusions: No significant difference was observed in prescribing pattern among doctors of various qualifications from both urban and rural setup and lack of knowledge about proper use of antibiotics was seen in community. Hence it is essential to create awareness by means of public education programmes, media and CME targeting both rural and urban areas.


Keywords


Antibiotic use, Self medication, Prescribing pattern, Antibiotic resistance

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References


Raghunath D. Emerging antibiotic resistance in bacteria with special reference to India. J Biosci 2008;33:593-603.

Gupta SK, Gupta P, Sharma P, Shrivastava AK, Soni SK. Emerging and re-emerging infectious diseases future challenges And Strategy. J Clin Diagn Res 2012;6:1095-100.

Aleykutty NA, Jayakar B, Suresh P, Leena PN, Mathews SM. Effect of regulations on the appropriate use of antibiotics. Int J Pharma Bio Sci 2011;2:32-5.

Preeth M, Shobana J. Study of prescription pattern of antibiotics used in the management of various infectious diseases in Andhra Pradesh. Int Res J Pharm 2011;2:112-5.

Mathew BS, Fleming DH, Gupta M, Kumar R, Kumar D, Chandy SJ, Balraj V. An objective measure of antibiotic use for febrile illness in a rural pediatric population using high performance liquid chromatography. Indian J Med Res 2010;131:723-5.

Kumar AP, et al. Students knowledge of antibiotics a cross sectional study of students in Tamil Nadu. Int J Pharm Pharm Sci 2010;3:232-3.

Varghese RT, Das R. Antimicrobial drug resistance in India, Possible causes. Asian Stud Med J 2010;1:151-4.

Shamshy K. Drug utilization of anti microbial drugs in pediatrics population in a tertiary care hospital in Erode, Tamil Nadu, India. Int J PharmTech Res 2011;3:1530-6.

Janaki R. Torvi, Dambal S. Drug prescription pattern in Pediatric outpatient clinic in a tertiary hospital. Curr Pediatr Res 2011;15:77-80.

Global Antibiotic Resistance Partnership-India (GARP-India). Situation analysis- Antibiotic Use and Resistance in India. Global Antibiotic Resistance Partnership-India National Working Group, March-2011. Available at http://www.cddep.org/sites/cddep.org/files/publication_files/India-report-web.pdf. Accessed 9 March 2012.

Peripi SB, Thadepalli VG, Khagga M, Tripuraribhatla PK, Bharadwaj DK. Profile of antibiotic consumption, sensitivity and resistance in an urban area of Andhra Pradesh, India. Singapore Med J 2012;53:268-72.

Khan NA, Abid M, Maheshwari KK, Kaviarasan PK, Mohanta GP. Antibiotic Prescribing Pattern in Department of Dermatology of a Teaching Hospital in Tamil Nadu. Indian J Pharm Pract 2010;3:18-21.

Moorthi1 C, Paul PR, Srinivasan A. Irrational use of antibiotics in paediatric prescriptions: A pilot study at community pharmacy in Erode City. Der Pharmacia Lettre 2011,3:171-7.

Shashikala, Kanungo R, Srinivasan S, Devi S. Emerging resistance to carbapenems in hospital acquired Pseudomonas infection: A cause for concern. Indian J Pharmacol 2006;38:287-8.

Bartoloni A, Cutts F, et al. Patterns of antimicrobial use and antimicrobial resistance among healthy children in Bolivia. Trop Med Int Health 1998;3:116-23.

World Health Organization. Promoting rational use medicines. Report of the Intercountry Meeting New Delhi, India, 13-15 July 2010. Available at http://www.searo.who.int/LinkFiles/Meetings_SEA-Drugs-161.pdf. Accessed 23 April 2012.

World Health Organization. Community-Based Surveillance of Antimicrobial Use and Resistance in Resource-Constrained Settings. Report on five pilot projects. WHO/EMP/MAR/2009.2. Available at http://www.who.int/medicines/publications/who_emp_2009.2/en/index.html. Accessed 18 January 2012.

Holloway K. Progress in the Rational Use of Medicines. Available at http://www.inrud.org/documents/upload/INRUD_News_Vol19_No1_Jul2009_Final.pdf. Accessed 18 January 2012.

Subbalaxmi MV, Lakshmi V, Lavanya V. Antibiotic Resistance - Experience in a Tertiary Care Hospital in South India. J Assoc Physicians India 2010;58 Suppl:18-22.

Bharathiraja R, Sridharan S, Chelliah LR, Suresh S, Senguttuvan M. Factors affecting antibiotic prescribing pattern in pediatric practice. Indian J Pediatr 2005;72:877-9.

Ganguly NK, Arora NK, Chandy SJ, Fairoze MN, Gill JP, Gupta U, et al. Rationalizing antibiotic use to limit antibiotic resistance in India. Indian J Med Res 2011;134:281-94.

Sivagnanam G, Thirumalaikolundusubramanian. P, Mohanasundaram.J. A survey on Current attitude of practicing physicians upon usage of antimicrobial agents in southern part of India. MedGenMed 2004;6:1.

Paul R, Sadiq S. A Prospective Study on Usage of Cephalosporins in Hospitalized Patients. IJPI’s J Hosp Clin Pharm 2011;1:5.

Ahmad A, Parimalakrishnan S, Patel I, et al. Evaluation of Self-Medication Antibiotics Use Pattern among patients Attending Community Pharmacies in Rural India, Uttar Pradesh. J Pharm Res 2012;5:765-8.

Balamurugan E, Ganesh K. Prevalence and pattern of self medication use in coastal region of South India. BJMP 2011;4:a428.