A case of refractory multiple myeloma

Authors

  • Ritesh Vekariya Department of Medicine, C.U. Shah Medical College and Hospital, Surendranagar 363001, India
  • Vishal Satadiya Department of Medicine, C.U. Shah Medical College and Hospital, Surendranagar 363001, India
  • Manish Bavaliya Department of Medicine, C.U. Shah Medical College and Hospital, Surendranagar 363001, India
  • Shyam Shah Third M.B.B.S., C.U. Shah Medical College and Hospital, Surendranagar 363001, India

Keywords:

M band, Pathologic fracture, Plasma cell cancer

Abstract

Multiple myeloma is a plasma cell cancer in which antibody-producing plasma cells grow in an uncontrolled and invasive way. The known incidence of multiple myeloma in India ranges from 0.5 to 1.2 per 100,000 & is a rare in India. It usually occurs in persons older than 55 years and the ratio of men: women is 3:2. Multiple myeloma affects the bones, immune system, kidneys and red blood cell count. We report a case of refractory multiple myeloma.

References

Longo DL. Plasma cell disorders. In: Fauci AS, Braunwald E, Isselbacher KJ, et al, editors. Harrison's Principles of Internal Medicine. 14th Ed. New York: McGraw Hill; 1998:712-3.

Küppers R, Klein U, Hansmann ML, Rajewsky K. Cellular origin of human B-cell lymphomas. N Engl J Med 1999; 341:1520-9.

Klausner JD, Freedman VH, Kaplan G. Thalidomide as an anti-TNF-alpha inhibitor: implications for clinical use. Clin Immunol Immunopathol 1996; 81:219-23.

Alexanian R, Dimopoulos MA, Delasalle K, Barlogie B. Primary dexamethasone treatment of multiple myeloma. Blood 1992; 80:887-90.

Quesada JR, Alexanian R, Hawkins M, Barlogie B, Borden E, Itri L, et al. Treatment of multiple myeloma with recombinant alpha-interferon. Blood 1986; 67:275-8.

Singhal S, Mehta J, Desikan R, Ayers D, Roberson P, Eddlemon P, et al. Antitumor activity of thalidomide in refractory multiple myeloma. N Engl J Med 1999; 341:1565-71.

The EUROCARE-4 database on cancer survival in Europe. Available at http://www.eurocare.it/Results/tabid/79/Default.aspx#longsurv0002. Accessed 2 August 2012.

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Published

2017-02-03

How to Cite

Vekariya, R., Satadiya, V., Bavaliya, M., & Shah, S. (2017). A case of refractory multiple myeloma. International Journal of Basic & Clinical Pharmacology, 1(1), 41–42. Retrieved from https://www.ijbcp.com/index.php/ijbcp/article/view/1396

Issue

Section

Case Reports