A retrospective study on drug utilization in patients with acute exacerbation of bronchial asthma in adults at tertiary teaching hospital in Bidar

Authors

  • Jyothi D. B. Department of Pharmacology, Associate professor, Bidar Institute of Medical Sciences, Bidar, Karnataka, India
  • Gajanan P. Kulkarni Department of Pharmacology, Associate professor, Bidar Institute of Medical Sciences, Bidar, Karnataka, India

DOI:

https://doi.org/10.18203/2319-2003.ijbcp20170335

Keywords:

Bronchial asthma, Beta-2 agonist, Drug utilization studies

Abstract

Background: Drug utilization plays a role in helping the health care system to understand, interpret and improve the drug use and continuous quality improvement. It plays an essential part of pharmaco Epidemiological studies.

Methods: 100 prescriptions from patients with established diagnosis of acute exacerbation of Bronchial asthma were assessed from the Department of Pulmonary Medicine and the data gathered was analysed using MS Excel.

Results: Majority of the prescriptions irrespective of severity received inhalation β2 agonist (formoterol) as a bronchodilator. Nebulization route was given for managing the acute exacerbations followed by inhalation route. Hydrocortisone was prescribed to all patients for managing acute Exacerbations. Montelukast was used an adjuvant therapy. Most of them were prescribed combination therapy. Theophylline was prescribed among all the methylxanthines.

Conclusions: β2 agonists Combinations and corticosteroids are the most commonly prescribed combination drugs for asthma followed by methylxanthines. The most commonly prescribed asthmatic Medication in combination therapy was inhaled salbutamol with ipratropium followed by intravenous Hydrocortisone and oral Montelukast. The most commonly prescribed methylxanthine was intravenous Theophylline. Nebulization was preferred route to tackle the acute exacerbation of asthmatic symptoms.

References

Shimpi RD, Salunkhe PS, Bavaskar SR, Laddha GP, Kalam A, Patel AK. Drug utilization evaluation and prescription monitoring in asthmatic patients, Int. J. Pharm. Bio. Sci. 2012;2(1):117-12.

Varkey S, Sen S. Prescribing patterns of corticosteroids in Pulmonology Department, IJPTP. 2012;3:334-7.

Boon AN, Colledge NR, Brain R. Respiratory Disease. Walker Principles and practice of Medicine Davidson’s 20th ed. Elseveir Limited; 2006:670.

Pinal DP, Patel RK, Patel NJ. Analysis of prescription pattern and drug utilization in asthma therapy, IRJP. 2012;3(7):257-60.

Sun HL, Kao YH, Chou MC, Lu TH, Lue KH. Differences in the prescription patterns of anti-asthmatic medications for children by paediatricians, family physicians and physicians of other specialties, J. Formos. Med. Assoc. 2006;105(4):277-83.

International consensus report on diagnosis and treatment of asthma. National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, Eur. Respir. J. 1992;5(5):509-11.

Ungar WJ, Coyte PC. Prospective study of the patient level cost of asthma care in children, Pediatr. Pulmonol. 2001;32:101-8.

Cochrane GM. Compliance and outcomes in patients with asthma, Drugs. 1996;52:12-9.

NIH, Guidelines for the Diagnosis and Management of Asthma, National Institutes of Health (NIH), Bethesda; 1997:41.

Reddel HK. Global Strategy for Asthma Management and Prevention, Global Initiative for Asthma; 2014;57-66.

Thamby SA, Juling P, Xin BTW, Jing NC. Retrospective studies on drug utilization patterns of asthmatics in a Government hospital in Kedah, Malaysia, Int. Curr. Pharm. J. 2012;1(11):353-60.

Sayadeda K, Ansari NA, Ahmed QS, Upadhyay P, Dey S, Madhwar A. Drug utilization study of antiasthmatic drugs in paediatric age group in a tertiary care teaching hospital, Bareilly, UP India, Int. J. Univ. Pharm. Biosci. 2013;2(3):145-56.

Drugs used in the treatment of asthma, in: J.U. Bradley, M.L. Lawrence (Eds.), Goodman and Gillman’s The Pharmacological Basis of Therapeutics, Mc Graw Hill Publishers and Distributors, New York; 2006:717-773.

Akram MF, Nasiruddin M, Ahmad Z, Khan RA.

Doxofylline and theophylline: a comparative clinical study, J. Clin. Diagn. Res. 2012;6(10):1681-4.

Rajathilagam T, Sandozi T, Nageshwari AD, Paramesh P, Jamunarani R. Drug utilization study in bronchial asthma in a tertiary care hospital, Int. J. Pharm. Appl. 2012;3(2):297-305.

Downloads

Published

2017-01-28

How to Cite

D. B., J., & Kulkarni, G. P. (2017). A retrospective study on drug utilization in patients with acute exacerbation of bronchial asthma in adults at tertiary teaching hospital in Bidar. International Journal of Basic & Clinical Pharmacology, 6(2), 389–392. https://doi.org/10.18203/2319-2003.ijbcp20170335

Issue

Section

Original Research Articles